A huge gamble (forgive the pun) spending money on those for two reasons: firstly we don’t know how Google will treat the “.ME” extension – it has no local search option so it will probably compete for SERPS with .com and .net and that puts it at a big disadvantage. Secondly, .ME is really there for “personal” sites, so I guess over time we could find the generic terms devalued and unable to compete with commercial sites for commercial searches.