Yes it is posible. You simply change the account details and payment details within your affilate control panel. then hand over the username and password to the new owner who changes the password. We’ve done it several times.
Finding a buyer, like GoodIdeasNoTime (nice name btw) says, is a different matter. To sweeten the deal you could offer to make up any shortfall in earnings after a period of say 12 months or 18 months.