I would agree that poker has made it past the tipping point and is way too mainstream now for a prohibition to stop it.
A quick anecdote, was talking with a friend of mine who has played poker for the past 20 years and he was commenting how his family always kind of looked down on him for doing so (from the conservative midwest). But, since the popularity boom of poker, his family is now coming to him and asking advice on how to play. An interesting turn of events for sure. Just goes to show that once people understand something like poker more, the less taboo it becomes.